The association between inflammation, obesity and elevated blood pressure in 16-25-year-old females

AK Subasinghe; JD Wark; A Gorelik; ET Callegari; SM Garland

Journal article

The association between inflammation, obesity and elevated blood pressure in 16-25-year-old females

AK Subasinghe, JD Wark, A Gorelik, ET Callegari, SM Garland

Journal of Human Hypertension | SPRINGERNATURE | Published : 2017

DOI: 10.1038/jhh.2017.33

Abstract

There is evidence to show an association between inflammation, obesity and elevated blood pressure. However, there is limited data for this relationship in adolescent females. We aimed to investigate the association between high sensitivity C-reactive protein (hs-CRP) and elevated blood pressure in young Australian females. Women aged 16-25 years living in Victoria were randomly recruited via targeted Facebook advertising. Socio-demographic information was collected via a web-based questionnaire. Anthropometric and blood pressure measurements were conducted by trained staff. Hs-CRP was assessed using the Abbott Architect assay. The demographic data were collected from 639 females (mean ± s.d..

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University of Melbourne Researchers

John Wark Author

Alex Gorelik Author

Suzanne Wark Author

Emma Callegari Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

We thank Melbourne Health Pathology and Ashwini Kale for collecting visceral data from participants. We also thank the research nurses, students and other staff who helped collect the data for the YFHI and Safe-D studies, and also the participants, without whom the studies would not have been possible. This work was supported by grants from the National Health and Medical Research Council (Program Grant #568971 and Project Grant #APP1049065).